Is abdominal pain a side effect of methotrexate?
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4 min read
According to Drugs.com, gastrointestinal issues including nausea and abdominal pain are very common side effects associated with methotrexate. Patients undergoing treatment for conditions like rheumatoid arthritis and psoriasis often experience varying degrees of abdominal discomfort, which can range from mild upset to more severe pain. It is a well-documented side effect caused by the drug's mechanism of action, which can affect rapidly dividing cells, including those lining the digestive tract.
