Can prednisone make myasthenia worse? Understanding the paradoxical effect
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4 min read
While corticosteroids like prednisone are a cornerstone of myasthenia gravis (MG) treatment, a paradoxical initial worsening of symptoms can occur in 25–75% of patients, particularly during the first two weeks of high-dose therapy. This phenomenon, often called 'steroid dipping,' is a well-known risk that requires careful management by healthcare professionals.