Which Microbe Is Susceptible to Sulfonamides? An Overview of Antimicrobial Action
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5 min read
Over 70% of sulfonamide-resistant isolates of pathogenic E. coli in one study from pigs could not be explained by known resistance genes, highlighting the complex and evolving nature of antimicrobial resistance. These foundational synthetic antibiotics act by disrupting folate synthesis in a range of microorganisms, answering the question of which microbe is susceptible to sulfonamides. However, their effectiveness is limited by widespread resistance, making targeted use, often in combination with other agents, essential today.