Tag: Microbiology

Over 90% of ampicillin resistance in *E. coli* is due to the production of TEM-1 beta-lactamase. Understanding **how does beta-lactamase work** is crucial to developing strategies against the growing threat of antimicrobial resistance.

Cell wall biosynthesis inhibitors have been one of the most successful classes of antibiotics in medical history, with the discovery of penicillin marking a new era of antimicrobial chemotherapy in the 1940s. These crucial medications, known as cell wall inhibitors, work by disrupting the formation of a critical structural component in many pathogenic microbes, ultimately leading to their destruction.

Tetracycline is a broad-spectrum antibiotic that has been used since the 1950s to treat a wide array of bacterial infections. The primary function of tetracycline is to stop the growth and spread of bacteria by interfering with their ability to produce essential proteins. This makes it an effective tool against numerous pathogens, though its widespread use has led to increasing concerns about antibiotic resistance.