Tag: Minimal change disease

Reports indicate that drug-induced kidney injury accounts for a significant number of acute kidney injury (AKI) cases, and numerous medications can cause nephrotic syndrome. This serious kidney disorder is characterized by damage to the tiny blood vessels in the kidneys (glomeruli), leading to excessive protein leakage into the urine.

Nephrotic syndrome is often caused by an immune system malfunction, which is why a potent immunosuppressant like cyclophosphamide is sometimes used for treatment. This chemotherapy agent is deployed primarily in cases of frequently relapsing or steroid-dependent nephrotic syndrome, offering an alternative to prolonged steroid use.