Tag: Molecular interactions

According to molecular dynamics simulations and NMR experiments, sugars and caffeine *do* interact in beverages through a process of molecular stacking, which affects their distribution and solubility. This interaction fundamentally changes how they behave in solution, providing a much more complex answer to the question: **Does caffeine bind to sugar**?.

Over 90% of the most frequently prescribed drugs bind to proteins in the bloodstream, highlighting the central role of these interactions in medicine. Understanding **how do drugs interact with proteins?** is fundamental to modern pharmacology, as these molecular relationships determine a drug's therapeutic effect, its journey through the body, and potential side effects.

Over 50% of the drugs on the market today exert their effects by targeting G protein-coupled receptors (GPCRs). The term that specifically describes the precise molecular and biochemical interactions of how these drugs work at their main drug targets is known as the **mechanism of action** (MoA).