Tag: Monoamines

Originally hailed for its ability to lower blood pressure, reserpine's dramatic impact on mental health and motor function led to a rapid decline in its use. But **what does reserpine do to the brain** at a neurochemical level to produce such profound effects, including sedation, depression, and parkinsonism? Its primary mechanism is the irreversible blocking of a key transporter for monoamine neurotransmitters.

During a 'fight or flight' response, catecholamine hormones are released into the body in response to physical or emotional stress [1.5.3]. This essential function raises the core question for understanding their impact: what class of chemicals are catecholamines?