Tag: Morphine equivalence

As a partial opioid agonist with high receptor affinity, buprenorphine's pharmacology is distinct from traditional opioids, meaning that a simple conversion ratio often fails to capture its full clinical picture. This article explores what is a buprenorphine equivalent to, detailing how its effects differ depending on context and route of administration.

Oral oxymorphone is an opioid analgesic roughly three times more potent than oral morphine and is indicated for the relief of moderate to severe pain [1.3.3, 1.3.5]. Answering the question of **what is 3 times more potent than oral morphine** requires a deep dive into pharmacology.