Tag: Most expensive drug

As of late 2024 and into 2025, the one-time gene therapy Lenmeldy (atidarsagene autotemcel) for metachromatic leukodystrophy holds the title of the most expensive infusion drug, with a staggering list price of $4.25 million. This represents a new peak in the rapidly evolving landscape of ultra-high-cost pharmaceuticals, dominated by groundbreaking gene therapies for rare genetic diseases.

Priced at $4.25 million for a single infusion, Kyowa Kirin's Lenmeldy is currently the most expensive drug substance in the world. This one-time gene therapy is a groundbreaking treatment for the ultra-rare genetic disorder metachromatic leukodystrophy (MLD), highlighting the high costs associated with advanced therapeutic innovation.

As of March 2024, the world's most expensive drug is Lenmeldy, a one-time gene therapy injection priced at $4.25 million [1.6.8, 1.2.4]. This article answers: **What is the richest injection in the world?**, exploring the medications commanding multi-million dollar price tags.

With a price tag of **$4.25 million**, Lenmeldy holds the title for the world's most expensive medical injection [1.4.2]. This one-time gene therapy treats metachromatic leukodystrophy (MLD), a rare, fatal genetic disorder affecting about one in 40,000 Americans [1.4.2, 1.7.6].