How does tubocurarine cause paralysis? Unpacking the mechanism of a prototype neuromuscular blocker
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4 min read
First isolated in 1897, d-tubocurarine is a benzylisoquinoline alkaloid derived from curare, which famously causes paralysis by blocking signals at the neuromuscular junction. This article explores *how does tubocurarine cause paralysis* by delving into its specific competitive antagonistic action on skeletal muscle receptors.
