Tag: Mthfr gene

While folic acid is widely recognized for its benefits in preventing birth defects and treating anemia, some individuals report feeling unwell after taking it. This is often linked to excessive doses or specific genetic variations that affect metabolism. The potential for negative side effects means it's crucial to understand your body's individual needs and response to this supplement.

While folic acid is considered safe for most people when taken in recommended doses, some individuals may experience gastrointestinal side effects. The concern, "Does folic acid make your tummy run?" is common, and research suggests that stomach upset, including loose stools or diarrhea, can occur, particularly with higher dosages or specific formulations.

According to a 2019 randomized, double-blind, placebo-controlled trial, L-methylfolate showed no significant benefit for core ADHD symptoms in adults. This mixed evidence raises a critical question for many seeking alternative treatments: Is L-methylfolate actually good for ADHD? The answer is nuanced and depends on a person's underlying genetics and treatment goals.

Multiple studies and systematic reviews have explored L-methylfolate's potential, with evidence suggesting that low serum and red blood cell folate levels are independent risk factors for major depressive disorder. L-methylfolate is the active form of folate and is being investigated to see if it can help depression, especially in cases where traditional treatments fall short.