What is the drug octagon?: A Guide to Multi-Parameter Optimization in Pharmacology
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3 min read
A successful drug must possess a delicate balance of many, often conflicting, properties [1.5.5]. The 'drug octagon' is a conceptual framework that helps answer the question, 'What is the drug octagon?' by visualizing the eight critical parameters that medicinal chemists must optimize for a compound to become an effective medicine.
