Tag: Muscle rigidity

While newer atypical antipsychotics like olanzapine have a lower propensity for movement side effects compared to older medications, rare but serious complications can arise. This raises the important question: can olanzapine cause muscle rigidity and what should patients know?

According to research, neuroleptic malignant syndrome, a rare but life-threatening reaction that includes severe muscle rigidity, is most commonly associated with antipsychotic medications but can occur with other agents. Knowing **what medications cause muscle rigidity?** is critical for patients, caregivers, and medical professionals to ensure prompt recognition and treatment of these serious conditions.

According to a review published on the NCBI Bookshelf, extrapyramidal symptoms (EPS) are among the most frequently observed and significant side effects of haloperidol, which can include muscle rigidity. This muscle stiffness is caused by the medication's mechanism of action, primarily the blockade of dopamine receptors in the brain, and can range from manageable discomfort to a severe, life-threatening condition.