Tag: Mycobacteria

In 2021, an estimated 450,000 cases of drug-resistant tuberculosis were reported globally, highlighting the need for potent antibiotics. So, what disease does rifampin treat? This vital drug is primarily used to combat tuberculosis and other serious bacterial infections, often as part of a multidrug regimen.

As the first new tuberculosis drug approved in over 40 years, bedaquiline (BDQ) has a novel mechanism of action that makes it invaluable for treating multidrug-resistant (MDR) strains. Understanding **what is the MOA of BDQ?** requires delving into its highly specific inhibition of a vital energy-generating enzyme in mycobacteria, leading to bacterial death.