Tag: Myeloproliferative neoplasms

As a potent inhibitor of DNA synthesis, Hydrea (hydroxyurea) is a crucial treatment for conditions characterized by an overproduction of blood cells, including platelets. So, what does hydrea do to platelets? It works by suppressing their production in the bone marrow to mitigate the risks associated with abnormally high counts.

In one study of patients with essential thrombocythemia, treatment with hydroxyurea resulted in a significant decrease in platelet count after a median of 30 days [1.2.1, 1.3.2]. Understanding **how long does it take for hydroxyurea to reduce platelets** involves several patient-specific factors.