Tag: Nafcillin

First approved by the FDA in 1970, nafcillin is a penicillinase-resistant penicillin antibiotic widely used to combat severe staphylococcal infections. To understand its specific clinical application, one must ask: **what is the indication of Nafcillin?** The drug is primarily indicated for treating infections caused by penicillinase-producing *Staphylococcus* species that are resistant to standard penicillin G.

Osteomyelitis, a serious bone infection, affects thousands annually and is becoming more complex due to rising antibiotic resistance. The question of what is the strongest antibiotic for osteomyelitis does not have a single answer; instead, treatment relies on identifying the specific causative bacteria and tailoring a powerful, targeted therapeutic regimen for each patient.

Although methicillin was first approved for use in 1960, it has been officially discontinued and is no longer commercially available for clinical treatment. This answers the question, **Is methicillin still available?**, and marks a significant chapter in the history of antibiotic development and resistance. Its withdrawal was driven by the rise of resistant bacteria and a high frequency of adverse side effects.