Tag: Nanomedicine

The concept of targeted drug delivery traces back to Paul Ehrlich's 'magic bullet' idea, a century-old vision of selectively targeting a pathogen without harming the host. Today, the realization of this vision is manifested in two primary targeted drug delivery systems: passive and active targeting. These systems utilize nanoscale carriers to concentrate therapeutic agents at a specific site in the body, optimizing drug effectiveness while drastically reducing side effects on healthy tissue.

The global pharmaceutical drug delivery market was valued at approximately US$1.9 trillion in 2023 and is projected to grow, with oral delivery methods accounting for over 55% of the market share. Understanding **what are the different types of drug delivery** is crucial for appreciating advancements in modern medicine.

Promising to revolutionize ocular medicine, nanotechnology-based eye drops offer enhanced drug delivery, yet understanding what are the side effects of nano eye drops is crucial for safe use. Clinical data for formulations like cyclosporine nanoemulsions point to common local effects, including blurred vision and eye irritation. This article details the potential risks and safety considerations for patients.

Amorphous forms of silica and silicates are generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) for oral delivery up to 1,500 mg per day. So, **is silica used in medicine?** Absolutely. This article explores its established and emerging roles, from its inert function as a pharmaceutical excipient to its revolutionary potential in advanced drug delivery systems.

While PEGylation has dramatically improved the stability and half-life of many biopharmaceuticals, a targeted literature review of PEGylated therapeutics reveals potential adverse outcomes, including increased drug clearance and decreased activity. Concerns regarding immunogenicity and patient safety have led to a critical re-examination of what are the drawbacks of PEGylation.

While silver has been used for medical purposes for thousands of years, modern research, particularly involving silver nanoparticles (AgNPs), has revealed specific anti-inflammatory effects, especially in topical applications for wounds and inflammation. However, the anti-inflammatory action is not universal across all forms of silver and depends heavily on factors like particle size, concentration, and context.

Globally, bacterial antimicrobial resistance was directly responsible for an estimated 1.27 million deaths in 2019, a figure projected to rise dramatically [1.9.1, 1.9.4]. This crisis fuels the need for novel therapeutic strategies, leading to the development of advanced systems that ask, **What is Trojan medication?** and how can it overcome these challenges.

Amorphous silica, also known as silicon dioxide ($SiO_2$), is a compound found naturally and widely used in the pharmaceutical industry, where it is generally recognized as safe (GRAS) by the FDA. Beyond its traditional role as a simple excipient, the answer to the question "What is silica used for?" now includes advanced applications like targeted drug delivery and tissue engineering.

With over 2.2 billion people globally suffering from vision impairment, nanotechnology offers a revolutionary approach to treatment [1.6.2]. So, what are nano drops used for? These advanced formulations enhance drug delivery, especially in ophthalmology, to treat conditions like dry eye, glaucoma, and more [1.3.3, 1.6.2].