Tag: Napqi

Acetaminophen overdose accounts for approximately 56,000 emergency department visits, 2,600 hospitalizations, and 500 deaths in the United States annually. Understanding **what are the four stages of acetaminophen toxicity** is crucial for timely intervention.

Each year in the United States, acetaminophen overdose is responsible for 56,000 emergency department visits and is a leading cause of acute liver failure [1.6.2, 1.6.4]. The key question is, **what is depleted when you take Tylenol?** The answer is glutathione, the body's master antioxidant [1.2.3, 1.2.4].

Over 50% of overdose-related acute liver failure cases in the United States are caused by acetaminophen, the active ingredient in Tylenol. This severe, toxic liver injury is distinct from true autoimmune hepatitis, a chronic disease where the body's immune system attacks its own liver cells.