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Tag: Narrow therapeutic window

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Why is theophylline no longer used? The decline of a former asthma and COPD drug

5 min read
By the late 1980s, theophylline generated sales of about $1 billion worldwide, but its use has since dramatically declined due to significant safety concerns and the emergence of superior treatments. This shift in medical practice directly answers the question, 'Why is theophylline no longer used?', making it a fourth-line or relegated therapy in modern respiratory care.