Is Estetrol Better Than Estradiol? A Detailed Pharmacological Comparison
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5 min read
Estetrol (E4), a natural estrogen produced by the human fetal liver, is now available in a combined oral contraceptive, raising the question: is estetrol better than estradiol (E2), the body's most potent estrogen during reproductive years [1.9.2, 1.8.1]? This new option offers a unique pharmacological profile.