Tag: Neurochemistry

According to research on ADHD medications, approximately 10% to 30% of adults do not respond to stimulant treatments, a statistic that leads many to ask, "Why do stimulants have no effect on me?". Understanding the complex interplay of biological and environmental factors is key to uncovering the answer.

For decades, the exact mechanism of action for the common pain reliever Tylenol (acetaminophen) was not fully understood, particularly its impact on the brain. Recent discoveries have shed light on a multi-faceted approach involving the central nervous system, where the drug works to reduce pain and fever through interactions with several key neurochemical pathways.

A recent meta-analysis found that approximately one in six or seven people (about 15%) experience symptoms directly attributable to stopping antidepressants [1.7.3]. This raises a critical question for many: **Does your brain go back to normal after sertraline?** This article explores the adaptive journey of the brain post-treatment.

According to a 2023 study published in *Science Advances*, healthy adults who took prescription stimulants like Adderall often showed decreased efficiency and accuracy despite feeling more focused. Taking Adderall without a medical need can have significantly different and more dangerous effects than its intended use in managing ADHD symptoms.

Scientific studies have long established that gabapentin does not directly increase acetylcholine release in the brain. The relationship between this medication and the body's cholinergic system is more complex, involving indirect signaling pathways rather than a simple boosting of the neurotransmitter.