Tag: Neurological symptoms

According to prescribing information, common neurological effects of Wellbutrin (bupropion) include insomnia, headaches, dizziness, and tremor. Understanding these and other potential side effects is vital for anyone taking this medication. The drug's unique mechanism of action as a norepinephrine-dopamine reuptake inhibitor (NDRI) sets its side effect profile apart from many other antidepressants, making awareness of what are the neurological symptoms of Wellbutrin crucial for patient safety.

While most people associate brain zaps with SSRI and SNRI antidepressants, a small number of people also report experiencing brain zaps when tapering off or discontinuing Wellbutrin (bupropion). These are typically described as electric-shock sensations in the head, often occurring during movement or periods of rest.

In a 2024 survey, over 75% of people tapering off or discontinuing an antidepressant reported experiencing **head zaps**, a common symptom of antidepressant discontinuation syndrome. This unsettling phenomenon can feel like a quick electrical jolt inside the brain, prompting concern and a search for answers.