Tag: Neurotherapeutics

Historically, it was believed that most molecules, especially larger ones like peptides, could not pass the blood-brain barrier (BBB). However, modern pharmacology demonstrates that some peptides can and do cross this formidable barrier through specialized transport mechanisms, opening new avenues for neurological drug delivery.

Did you know that approximately 98% of all small molecule drugs do not cross the blood-brain barrier, highlighting the significant challenge of which drugs don't cross the blood-brain barrier in medicine. This highly selective physiological barrier is designed to protect the central nervous system, but it also presents a major obstacle for delivering therapies to the brain.