Tag: Neurotoxicity

Case reports have documented serious neurotoxic effects, including gait disturbances and confusion, in elderly patients who took bupropion and amantadine together. Because of this, understanding the severe risks associated with taking bupropion and amantadine together is critically important before considering this combination.

While methotrexate is a cornerstone for treating conditions like rheumatoid arthritis and psoriasis, mood and behavioral changes are documented, albeit rare, side effects. Some patients, including children, have experienced symptoms like irritability and depressed mood that resolve upon stopping the medication.

The cerebellum is particularly susceptible to toxic insults, with numerous medications documented to cause cerebellar dysfunction. A wide range of drugs, from common antiepileptics like phenytoin to chemotherapeutic agents, can induce a potentially devastating cerebellar syndrome characterized by impaired coordination and balance. Understanding what drugs cause cerebellar dysfunction is crucial for early detection and management.

According to a 2016 study published in *Neurology*, antibiotics may be linked to delirium and other brain problems more often than previously thought. The elderly are particularly susceptible to this side effect, prompting the critical question: **Can antibiotics cause confusion in the elderly?** This article explores the specific risks and provides vital information for patients and caregivers.

While frontotemporal dementia (FTD) is primarily a neurodegenerative disease with genetic and pathological roots, certain medications and long-term substance abuse can induce cognitive and behavioral symptoms that closely mimic FTD. It is crucial to understand these distinctions, as drug-induced cognitive decline may be reversible in some cases, unlike the progressive nature of true FTD. This article explores the relationship between various drugs, substance misuse, and FTD-like syndromes.

Reports from patients show that headaches and a feeling of 'methotrexate fog' are common side effects, typically occurring the day after a dose. Understanding **why does methotrexate cause headaches** is key to managing this and other related side effects.

Recent research indicates that antibiotic-associated encephalopathy (AAE), a form of delirium, may be more common than previously recognized by medical professionals. While the condition is often temporary, many individuals affected or their caregivers wonder: does delirium from antibiotics go away, and what is the typical recovery process?

While generally considered a safe antibiotic, one retrospective review of ceftazidime cases revealed that patients with neurotoxicity most frequently presented with confusion and myoclonus. This adverse effect, known as ceftazidime neurotoxicity, is a documented phenomenon in medical literature, especially affecting vulnerable populations.

According to one review, drug-induced peripheral neuropathy accounts for up to 4% of all neuropathy cases, with certain medications posing a significantly higher risk. The answer to "can nerve damage be caused by medication?" is a definitive yes, as it is a known side effect of many drug classes, from antibiotics to cancer treatments.

Research indicates that current use of systemic fluoroquinolone antibiotics can increase the risk of peripheral neuropathy by 47% [1.7.7]. While essential for fighting infections, some antibiotics carry a risk of neurological side effects. So, can antibiotics mess with your nerves? The answer is yes, for a subset of patients and with specific types of drugs.