Tag: Neutropenia

According to a 1993 study in *The New England Journal of Medicine*, the cumulative incidence of clozapine-induced agranulocytosis was 0.80% at one year, highlighting that the risk, while real, is a rare event. The potential for clozapine to cause agranulocytosis is the primary factor necessitating stringent blood monitoring for patients.

Approximately 20-30% of patients with schizophrenia are considered treatment-resistant, failing to respond to standard therapies [1.6.6, 1.6.7]. For these individuals, the crucial question is, **what class does clozapine belong to?** It is a unique atypical antipsychotic, recognized as the gold standard for this challenging condition [1.2.2].

Yes, capecitabine can cause a fever, and for chemotherapy patients, this can signal a serious medical concern such as neutropenia. In fact, reports from clinical trials and adverse event systems confirm that fever is a potential side effect associated with the use of this oral chemotherapy agent.

Clinical trial data show that infections, including urinary tract infections (UTIs), are a common side effect for patients taking Verzenio (abemaciclib). The medication can lead to a reduced white blood cell count, a condition known as neutropenia, which compromises the immune system and increases the overall risk of developing infections.

In clinical trials, the most common adverse reactions to riluzole were asthenia, nausea, and decreased lung function, highlighting the potential for significant side effects. This medication, while vital for managing amyotrophic lateral sclerosis (ALS), comes with important disadvantages that patients and healthcare providers must carefully consider.

According to instructions from leading medical centers, filgrastim (Neupogen) is given as a subcutaneous injection at a 45- to 90-degree angle. The specific angle for filgrastim injection depends on the amount of subcutaneous fat and is determined during patient training by a healthcare provider.

A short intravenous (IV) infusion of filgrastim typically takes between 15 and 30 minutes to administer, but the total time for the medication depends entirely on the route used. Understanding **how long does filgrastim take to administer** is crucial for patients and caregivers managing treatment schedules, as methods range from quick daily injections to extended infusions.

Filgrastim, a man-made protein used to boost white blood cell counts, is often prescribed after chemotherapy to reduce the risk of infection. With proper training from a healthcare professional, *can filgrastim be self-administered* by a patient or caregiver, providing more convenience and flexibility during treatment.

The average retail price for Fulphila is around $2,776, but cash prices with coupons can be as low as $2,046 for a 6 mg/0.6 mL syringe [1.2.8, 1.2.5]. This article details the various factors that answer the question: **How much does Fulphila cost in the US?**

In a landmark decision in June 2025, the U.S. Food and Drug Administration (FDA) officially eliminated the Clozapine Risk Evaluation and Mitigation Strategy (REMS) program, which had long governed its distribution. This major regulatory update directly answers the question, **is clozapine still available?**, by confirming its continued availability with substantially improved access for patients and clinicians.