Tag: Nicotinic receptor

Discovered and characterized extensively since the 1970s, the nicotinic receptor is one of the most well-understood membrane receptors at a structural and functional level. These ligand-gated ion channels play critical roles in rapid neural and neuromuscular communication throughout the body.

Rocuronium is a widely used nondepolarizing neuromuscular blocking agent, with a rapid onset of action that makes it highly useful for rapid sequence intubation. Understanding **how does rocuronium work** is crucial for healthcare professionals and provides insight into modern anesthetic techniques for achieving temporary muscle paralysis.

While historically marketed for smoking cessation, the FDA banned over-the-counter sales of lobeline hydrochloride-containing products in 1993 due to a lack of sufficient evidence supporting their effectiveness for this purpose. This natural alkaloid, derived from the *Lobelia inflata* plant, has a complex history and mechanism of action that continues to be of research interest.