Tag: Nitric oxide

Arginine Alpha-Ketoglutarate (AAKG) is a popular supplement, often used to potentially enhance athletic performance and support muscle function. Understanding how much AAKG per day is generally used is important for those considering this supplement.

Discovered as an endogenous polyamine in the mammalian brain in 1994, agmatine is naturally synthesized from the amino acid L-arginine. Research into what does agmatine do has revealed its intricate pharmacological profile, functioning as a neurotransmitter and neuromodulator with diverse effects across multiple organ systems.

A 2017 study on healthy middle-aged and older adults found that 12 weeks of curcumin supplementation increased vascular nitric oxide bioavailability, improving endothelial function. This evidence begs the question: Does curcumin increase nitric oxide? The answer is nuanced, involving a dual mechanism influenced by physiological context.

First used as an explosive, the medical benefits of nitroglycerin for treating angina were discovered by factory workers who experienced relief from chest pain. Today, understanding what is the mechanism of action of nitroglycerin is critical for its safe and effective use in cardiovascular medicine.

Chronic treatment with tadalafil has been shown to significantly improve flow-mediated dilation (FMD), a key measure of endothelial function, in men with increased cardiovascular risk. This improvement demonstrates that the medication's effects extend beyond its well-known applications, pointing to broader vascular benefits.

Observational studies involving millions of patient records have raised concerns about a potential link between long-term proton pump inhibitor (PPI) use and increased cardiovascular risk. This raises the critical question: can omeprazole cause bad circulation?

Studies show that low serum folate levels are associated with a significantly increased risk of fatal coronary heart disease [1.11.1]. This has led to extensive research asking: **does folic acid improve blood circulation** and overall cardiovascular health through its various metabolic roles?

Acetylcholine (ACh), a vital neurotransmitter, exhibits a dual role in the cardiovascular system [1.8.1]. The answer to whether **does acetylcholine cause vasoconstriction or vasodilation** is complex, as it depends on the health of the vascular endothelium and the specific receptors activated [1.4.2, 1.5.1].

Studies show that consuming beetroot juice can increase nitric oxide levels by 21% in as little as 45 minutes [1.2.1]. As a concentrated beetroot powder, the question arises: **does Super Beet boost nitric oxide** levels to deliver on its promises of improved circulation and energy?

Betaine, also known as trimethylglycine (TMG), is a compound naturally found in foods like beets and spinach that acts as a methyl donor. The question of *does betaine increase nitric oxide* is complex, with research suggesting both indirect mechanisms and conflicting human study results regarding circulating levels.