What are the antagonists for neurokinin 2 receptors?
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3 min read
The neurokinin 2 (NK2) receptor, a member of the tachykinin receptor family, is predominantly found on smooth muscle in the periphery, including the gastrointestinal, respiratory, and urinary tracts. A range of compounds, known as neurokinin 2 receptor antagonists, have been developed to block the action of the endogenous ligand neurokinin A (NKA) at these receptors, though many have failed to reach the market despite initial promise.
