Tag: Nmda antagonist

Methadone, a synthetic opioid, is chemically known as a chiral molecule, meaning it has two non-superimposable mirror-image forms called enantiomers. These two forms, R-methadone and S-methadone, are the two types of methadone that manifest in the clinical product, influencing its diverse effects on the body. While the drug is primarily used in a mixture for opioid use disorder (OUD) treatment and pain management, understanding the properties of its individual isomers provides deeper insight into its pharmacology.

Originally approved in the 1960s as an antiviral for Influenza A, amantadine's utility in treating Parkinson's disease was discovered serendipitously. The complex and dual-purpose **mechanism of action of amantadine** involves distinct pharmacological pathways to address different medical conditions, though its use for influenza is now discouraged due to widespread resistance.

Originally approved in 1966 as an antiviral medication for influenza A, the use of amantadine has evolved dramatically, with its primary applications now centered on neurological conditions like Parkinson's disease. However, it is no longer effective or recommended for treating the flu due to widespread viral resistance.