Tag: Nociception

According to the American Society of Anesthesiologists, anesthesia awareness, where a patient becomes conscious and may feel pain during surgery, occurs in only one or two of every 1,000 general anesthesia procedures. When properly administered, modern anesthesia ensures that the body does not consciously feel pain by preventing the brain from processing pain signals.

In 2021, an estimated 51.6 million U.S. adults experienced chronic pain, highlighting the critical need for effective pain management strategies [1.7.1]. A key concept in the pharmacology of pain relief is understanding **what is antinociceptive** and how it relates to blocking pain signals.