Tag: Non dihydropyridine

With the calcium channel blocker market valued at over $16.92 billion in 2025, millions rely on these drugs [1.9.3]. So, what is a very common adverse effect of all calcium channel blockers? The answer is linked directly to their primary mechanism of action: vasodilation [1.2.4].

Globally, elevated systolic blood pressure is the leading risk factor for death, accounting for 10.2 million deaths [1.3.7]. When lifestyle changes aren't enough, doctors often ask, 'Which is the safest calcium channel blocker to prescribe for conditions like hypertension?'

Calcium channel blockers (CCBs) are a widely prescribed class of medications for conditions like high blood pressure and angina [1.3.2]. A common question patients have is, 'Do all calcium channel blockers cause the same side effects?' The answer is no; side effects vary significantly between the different types.

Peripheral edema, or swelling, is a very common side effect of calcium channel blockers (CCBs), with an overall incidence rate of about 10.7% in patients taking these medications [1.6.2, 1.6.3]. So, what is the most common adverse effect of calcium channel blockers, and why does it occur?

One study on hypertensive patients with obstructive sleep apnea found that those using calcium channel blockers (CCBs) experienced a significant reduction in total sleep time by an average of 41 minutes [1.2.1, 1.3.1]. If you take these common medications, you may wonder: **do calcium channel blockers cause sleep problems?**