Tag: Norgestrel

In clinical trials for the over-the-counter progestin-only pill Opill, acne was reported as a common side effect. The important question, 'Does norgestrel cause acne?', hinges on the hormonal dynamics of this type of medication and how it interacts with an individual's skin.

Norgestrel is a synthetic progestin that has been used in oral contraceptives since 1966 [1.7.6, 1.3.6]. So, what is another name for norgestrel? It is also known chemically as dl-norgestrel or by various brand names depending on its formulation and whether it's sold alone or with estrogen [1.3.6].

Despite persistent concerns among users, clinical studies show limited evidence that progestin-only contraceptives like norgestrel cause significant weight gain. Any initial, temporary weight increase is often due to water retention, not fat gain, and typically resolves as the body adjusts.

An estimated 43.6% of women using hormonal contraception report experiencing mood changes, which is a major concern for those asking, 'Does norgestrel affect your mood?'. As a synthetic progestin, norgestrel can influence the brain's neurochemistry, leading to a variety of emotional and psychological side effects that vary significantly among individuals.

Most synthetic progestins used in hormonal contraceptives are derived from testosterone and retain varying degrees of androgenic activity [1.7.7]. Understanding which progesterone has the most androgenic effect, such as second-generation progestins like levonorgestrel and norgestrel, is key to managing potential side effects [1.7.3].

Norgestrel, a synthetic form of the hormone progesterone, primarily works in the body by preventing pregnancy through several key mechanisms. It is a progestin-only contraceptive, often referred to as a 'mini-pill,' and has recently become available over-the-counter for the first time in the United States.

In a historic shift for reproductive healthcare access, the U.S. Food and Drug Administration (FDA) approved norgestrel for over-the-counter (OTC) use in July 2023, making it the first daily oral contraceptive available without a prescription. The subsequent retail availability of Opill in early 2024 has expanded access to contraception, answering the common question, "Is norgestrel available in the USA?".

As an effective progestin-only birth control pill, norgestrel offers a contraceptive option for many people. However, it is not safe for everyone, and certain medical conditions, allergies, and lifestyle factors can prevent its use due to serious health risks.

Despite persistent fears, clinical trials found that weight gain was not a common side effect of Opill (norgestrel). While many users of hormonal birth control have concerns, most modern pills, including the over-the-counter Opill, are not linked to significant weight fluctuations.

Opill, the first FDA-approved over-the-counter birth control pill, contains the progestin norgestrel. While not a common side effect for everyone, hair loss is listed as a potential adverse reaction of Opill, particularly for individuals genetically sensitive to hormonal changes.