Tag: Novantrone

Mitoxantrone (Novantrone) was the first drug approved in the US for secondary progressive multiple sclerosis (SPMS), progressive-relapsing MS, and worsening relapsing-remitting MS. This potent chemotherapy drug functions as an immunosuppressant to help control the immune system's attack on the central nervous system in certain forms of MS.

First approved by the FDA in 1987 for acute myeloid leukemia, mitoxantrone is a potent medication used to treat several serious conditions, including aggressive forms of multiple sclerosis and advanced prostate cancer. Due to its significant risk profile, it is typically reserved for cases where other treatments have been ineffective.