Tag: Nuclear receptors

An estimated 34% of all FDA-approved drugs target a single superfamily of receptors known as G protein-coupled receptors (GPCRs) [1.7.3]. Understanding the answer to 'What are the different types of receptors in pharmacokinetics?' is crucial for grasping how medications work.

Approximately 90% of all drugs are cleared by metabolism, with the Cytochrome P450 (CYP450) enzyme family playing a dominant role [1.7.1, 1.8.1]. Understanding **what is the mechanism of action of an enzyme inducer** is crucial because these substances can significantly alter drug metabolism, affecting patient outcomes.

Estrogen-related receptors (ERRs) are central regulators of energy metabolism, and recent studies on synthetic ERR agonists like SLU-PP-332 show they can mimic the metabolic benefits of exercise [1.5.3, 1.6.2]. So, what is an ERR agonist? It's a molecule that activates these powerful receptors.