Tag: Numbing effect

Dried coca leaves contain approximately 0.6% cocaine, the principal alkaloid responsible for their well-known numbing effect [1.3.1]. For centuries, Andean cultures have chewed coca leaves, and a primary question for many is: **do coca leaves numb the mouth?** The answer lies in their complex pharmacology.

According to the drug manufacturer's prescribing information, the duration of action for Novocain (procaine) is relatively short, averaging between 1 to 1.5 hours, though individual and procedural factors heavily influence this. This guide addresses the common question, “how long will Novicane last?”, and explores why modern dental practice often favors different local anesthetics with more predictable and longer-lasting effects.