Tag: Omadacycline

Official patient instructions for the antibiotic Nuzyra (omadacycline) explicitly state to remain upright for at least 10 minutes after taking the medication. While this is a shorter period than required for some other tetracyclines, it remains a critical step to ensure safety and effectiveness.

Originally approved by the FDA in 2018 for serious infections, omadacycline is an aminomethylcycline antibiotic that represents a significant evolution in its class. It is crucial for clinicians and researchers to understand **what is the mechanism of action of omadacycline**, as it is designed to overcome many of the resistance challenges associated with older tetracyclines.

Clinical studies have demonstrated that the oral bioavailability of omadacycline can be reduced by up to 63% when consumed with a meal containing dairy, compared to a fasted state. This significant reduction in absorption is the critical reason why you can't eat with Nuzyra, as it directly impacts the medication's ability to effectively treat serious infections.