Tag: Ophthalmic administration

Over 90% of commercially available ophthalmic medications are delivered through eye drops due to their non-invasive nature and relative ease of use. The standard administration route for eye drops is topical application to the conjunctival sac, the pocket formed by the lower eyelid.

Less than 5% of a topically administered eye drop reaches the intraocular tissues, with the majority being lost to drainage or systemic absorption. Understanding what is the route of administration of eye drops is therefore critical for maximizing therapeutic effect and minimizing potential side effects.

In the United States, an estimated 4.22 million adults had glaucoma in 2022, a condition often managed by topical medication [1.2.2]. Knowing how is ocular medication administered is crucial for treating this and other eye conditions effectively and safely.