What is Oral DMT? Understanding the Powerful Psychedelic
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4 min read
Unlike other routes of administration, oral DMT is not psychoactive on its own because the body's natural enzymes, monoamine oxidases (MAOs), quickly inactivate it. To produce a psychoactive effect, oral DMT must be combined with a monoamine oxidase inhibitor (MAOI), such as in the traditional Amazonian brew ayahuasca. This combination allows the psychedelic compound to survive digestion and produce a profound, long-lasting experience.