Tag: Oral testosterone

Globally, the lifetime prevalence of anabolic-androgenic steroid use is 6.4% for males [1.9.2]. A primary concern for users and prescribers has been liver safety, begging the question: **Is oral testosterone hard on the liver?** The answer depends entirely on the type of oral testosterone in question.

According to the Endocrine Society, low testosterone affects up to 40% of men over the age of 45. This prevalence has led many to ask: **Do testosterone pills really work?** The answer depends entirely on whether you are referring to an FDA-approved prescription or an over-the-counter (OTC) supplement.

Hypogonadism, or low testosterone, affects an estimated 4 to 5 million men in the United States, yet only about 5% receive treatment [1.8.5]. The question for many is: **are oral testosterone pills effective** and safe for managing this condition?

For decades, men with low testosterone had few options beyond injections or topical gels, but a new generation of FDA-approved oral medications has made oral testosterone a safe and effective reality for many. These modern pills represent a significant pharmacological advancement, overcoming the liver toxicity issues that plagued older oral versions.

Approved by the FDA in 2022, Kyzatrex is an oral capsule used for testosterone replacement therapy in men diagnosed with specific types of hypogonadism. This provides a modern, needle-free alternative to traditional injections and gels for managing low testosterone.

According to a 2023 review, newer formulations of oral testosterone undecanoate are safer and more effective than older oral versions previously linked with liver toxicity. When considering what is the best oral testosterone pills, the answer is not one-size-fits-all, but depends on individual medical needs and lifestyle factors.