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Tag: Osteoclasts

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How do bisphosphonates treat hypercalcemia?

4 min read
Hypercalcemia of malignancy accounts for up to 90% of severe hypercalcemia cases in a hospital setting. In such instances, bisphosphonates are a primary therapy, working by powerfully inhibiting the bone-dissolving activity of osteoclasts. This therapeutic approach effectively lowers elevated blood calcium levels and manages related complications.