Tag: Overdose management

According to the National Institutes of Health, atropine overdose can lead to severe anticholinergic syndrome, characterized by a range of disruptive symptoms. The key question in managing such cases—what reverses atropine toxicity—points directly to the primary antidote, physostigmine, and a comprehensive strategy of supportive medical care.

Flecainide toxicity, though rare, has a reported mortality rate of up to 22.5% [1.2.2]. Knowing how to reverse flecainide toxicity is critical for emergency practitioners, as overdose can lead to life-threatening cardiac events and complete cardiovascular collapse [1.3.1, 1.2.6].

Overdoses of up to 4 mg in a single dose of semaglutide have been reported in clinical trials, but it is a critical safety point that no specific antidote exists to reverse its effects. This means that for individuals concerned about or experiencing adverse effects, management focuses on supportive care and the body’s natural elimination process.

Activated charcoal is used in emergency departments for certain poisonings and drug overdoses, though it is not a true chemical antidote. Instead, it works by trapping ingested toxins in the gastrointestinal tract to prevent their absorption into the bloodstream.