Is omeprazole a P450 inhibitor? Understanding its drug interaction profile
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4 min read
Omeprazole, a widely prescribed proton pump inhibitor (PPI), is a known inhibitor of the cytochrome P450 (CYP) enzyme system, most potently affecting the CYP2C19 isoenzyme. This interaction is of significant pharmacological interest because it can alter the metabolism of other medications, leading to potential drug-drug interactions that may affect treatment efficacy or increase the risk of adverse events.
