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Tag: Pain sensitivity

Explore our medication guides and pharmacology articles within this category.

Understanding What is a Paradoxical Effect of Opioids?

4 min read
For more than a century, clinicians have noted a baffling phenomenon in which patients on opioid pain medication experience a worsening of pain instead of relief. This paradoxical effect of opioids, known as opioid-induced hyperalgesia (OIH), is a serious and complex side effect of long-term opioid therapy. It is crucial for patients and healthcare providers to understand this condition to manage pain safely and effectively.