What is the biggest side effect of lamotrigine? Understanding the serious rash risk
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4 min read
Lamotrigine, a medication used for epilepsy and bipolar disorder, carries a black box warning from the FDA due to a rare but serious risk of developing a severe, life-threatening skin rash. For this reason, the most feared and potentially the biggest side effect of lamotrigine is the development of a severe cutaneous adverse reaction.