Tag: Pcv regimen

In a long-term study of patients with low-grade glioma, the addition of procarbazine-based chemotherapy to radiation therapy extended median overall survival from 7.8 years to 13.3 years [1.2.2]. This highlights the critical question: exactly how effective is procarbazine in modern oncology?

Approved for use in the United States in 1969, procarbazine remains a key chemotherapy drug used in combination regimens to treat advanced Hodgkin's lymphoma and certain brain cancers [1.7.3]. So, what does procarbazine do? It functions as an alkylating agent, slowing or stopping the growth of cancer cells [1.3.1].