Tag: Penicillinase resistant

About 90% of Staphylococcus aureus strains found in hospital settings are resistant to benzylpenicillin, highlighting the need for specialized medications. So, **is cloxacillin an antibiotic** designed to solve this problem? Yes, it is a key member of the penicillin family, engineered to combat these resistant bacteria.

First introduced in 1959, methicillin was a revolutionary semi-synthetic penicillin created to combat infections from penicillinase-producing bacteria, like *Staphylococcus aureus*. However, this vital drug was never manufactured for oral use because it is rapidly and extensively destroyed by gastric acid, making it ineffective if swallowed.