Tag: Peripheral edema

With the calcium channel blocker market valued at over $16.92 billion in 2025, millions rely on these drugs [1.9.3]. So, what is a very common adverse effect of all calcium channel blockers? The answer is linked directly to their primary mechanism of action: vasodilation [1.2.4].

Approximately 10–25% of people who take amlodipine develop swelling in their feet or ankles. This common, yet often bothersome, side effect leads many patients to ask the crucial question: does amlodipine cause swelling?

An estimated 10.7% of patients on calcium channel blockers (CCBs) experience peripheral edema, or swelling, a side effect that varies significantly depending on the specific drug. To answer, 'Do all calcium channel blockers cause peripheral edema?' is misleading; the risk is not equal across the board, with some classes having a substantially higher incidence than others.

Levetiracetam, widely known by its brand name Keppra, is an anti-seizure medication used by millions to manage epilepsy [1.7.2]. While effective, patients and caregivers often ask: **Can Keppra cause swelling?** The answer is yes, this medication can lead to different types of swelling, ranging from uncommon to rare but serious reactions [1.2.1, 1.2.3].

Up to 25% of people taking amlodipine may experience swelling in their feet and ankles, a known side effect called peripheral edema. While this is a common occurrence, it is fundamentally different from true lymphedema, a chronic and distinct condition. This article clarifies how **can amlodipine cause lymphedema**, exploring the nuance between drug-induced edema and lymphatic system dysfunction.

Peripheral edema, or swelling, is a common side effect of calcium channel blockers (CCBs), affecting up to 70% of patients on high-dose dihydropyridine agents. If you're experiencing swelling from your medication, understanding how do you reduce swelling from calcium channel blockers is crucial for improving your comfort and adherence to treatment.

According to the package insert for Amantadine Capsules, peripheral edema, or swelling of the extremities, is a frequently reported adverse reaction, occurring in 1% to 5% of patients. This means that experiencing swollen ankles is a documented side effect when taking the medication.

Spironolactone is a potassium-sparing diuretic that is often prescribed to reduce fluid retention, or edema, in conditions like heart failure, liver disease, and nephrotic syndrome. However, some people may experience new or worsening fluid buildup in the ankles and feet, raising the question: Does spironolactone cause ankle swelling?. The answer is complex, as swelling while on the medication could be a sign of a new or different issue, not just a side effect.

With millions of adults experiencing edema, a common prescription for fluid retention and swelling is the diuretic furosemide. When considering **what diuretic is good for swollen feet**, the ideal choice depends on the underlying cause and severity of the fluid buildup, which a healthcare provider can diagnose and address.

MedlinePlus and the NHS both list cold hands and feet as a known side effect of metoprolol. While a common occurrence, many patients are not fully aware of how or why the medication affects their extremities and what can be done to manage the symptoms. This guide addresses the question: 'Can metoprolol affect your feet?', detailing the specific side effects, their mechanisms, and practical management tips.