Tag: Permanent damage

Approximately one in four people discontinue Topamax treatment due to intolerable side effects. While many side effects are temporary and resolve upon stopping the medication, some serious and rare risks can lead to long-term or permanent health damage, prompting the critical question: Can Topamax cause long-term damage?.

The risk of permanent nerve damage from an epidural is estimated to be between 1 in 23,500 and 1 in 240,000 cases [1.2.1, 1.2.2]. While this pain relief method is overwhelmingly safe, the question remains: **can an epidural cause permanent damage?**

Propofol is used for approximately 95% of sedation cases for procedures like colonoscopies, but can propofol cause permanent damage under certain conditions, particularly prolonged high-dose infusions? The answer hinges on the dose, duration, and patient-specific factors, with serious complications primarily tied to the rare Propofol Infusion Syndrome (PRIS).

Chronic NSAID use is associated with thousands of hospitalizations and fatalities each year, particularly among older adults. This raises a critical question for many: **Can NSAIDs cause permanent damage?**

While paliperidone is a highly effective medication for treating schizophrenia and schizoaffective disorder, long-term use carries certain risks. The primary concern regarding permanent damage revolves around conditions like tardive dyskinesia, a potentially irreversible movement disorder.