Tag: Personalized medicine

Adjuvant therapy has become a cornerstone of modern cancer treatment, representing a proactive strategy to improve long-term patient outcomes. The best reason to administer adjuvant therapy is to eradicate microscopic cancer cells that remain after primary treatment, effectively reducing the risk of cancer recurrence.

Approximately 30% of the U.S. population carries a CYP2C19 loss-of-function allele, directly impacting how effectively their body activates the antiplatelet drug clopidogrel. This metabolic process is crucial for preventing dangerous blood clots in at-risk individuals, making the question 'Is clopidogrel activated by CYP2C19?' central to personalized medicine.

Approximately six in ten U.S. adults currently take at least one prescription drug, but for those seeking optimal treatment, the question of what's the best prescription drug is complex and has no single answer.

According to the Crohn's & Colitis Foundation, hundreds of thousands of people in the U.S. live with Crohn's disease, and treatment options have significantly expanded in recent years. However, there is no single answer to the question, "What is the best drug to treat Crohn's disease?" as the optimal therapy is customized for each individual based on their specific condition.

According to the FDA, grapefruit juice can affect the metabolizing rates of some medicines by altering a specific drug-metabolizing enzyme, which is a prime example of **how do drug interactions affect metabolism**. This complex process can significantly alter how medications work in the body, potentially increasing the risk of serious side effects or reducing a drug's effectiveness.

Pharmacogenomics experts estimate that genetic factors account for 20 to 95 percent of patient variability in drug response. Understanding what are the 5 factors affecting drug metabolism is critical for optimizing medication therapy and preventing adverse reactions, as a drug's effectiveness can vary significantly from person to person.

Genetic factors alone can account for 20-95% of individual variability in response to some medications, highlighting the complexity of therapeutic outcomes. A patient's unique genetic makeup, coupled with other physiological conditions and concurrent drug interactions, determines what are three factors that can affect a medication action, ultimately impacting its efficacy and safety profile.

Approximately 1 in 300 people have a complete deficiency of the thiopurine S-methyltransferase (TPMT) enzyme, putting them at high risk for severe drug toxicity. This article explains what is TPM in medicine by focusing on the crucial role of TPMT in personalizing treatment.

According to the United States Pharmacopeia (USP), hundreds of thousands of sterile medications are prepared annually to meet individual patient needs that cannot be addressed by commercially available products. This vital process gives rise to a **CSP drug**, or Compounded Sterile Preparation, a crucial and customized form of medication that is essential for many patients' health.

With superior bioavailability compared to oral supplements, the administration schedule for CoQ10 injection is not standardized but is instead a highly personalized protocol. How often you should get a CoQ10 injection depends on your individual health needs and the specific plan devised by your healthcare provider.