Tag: Pharmaceutical history

Over its 175-year history, Pfizer has evolved from a small chemical manufacturer to a global biopharmaceutical leader, delivering breakthroughs that have changed billions of patient lives. This extensive history showcases exactly what has Pfizer achieved in the fields of medications and pharmacology, with impacts spanning from antibiotics to cutting-edge cancer treatments.

Over 10,000 people were affected by subacute myelo-optic neuropathy (SMON) in Japan between 1957 and 1970, with the resulting investigation conclusively linking the disease to the oral administration of enteroquinol. This connection led to the drug's global ban for oral use and a re-evaluation of drug safety standards worldwide.

Though it was only available for a short time in the mid-2000s, the question **what is Sultrin?** was once relevant to patients seeking treatment for bacterial vaginitis. Sultrin was a brand name for a discontinued triple sulfa vaginal cream used to treat specific bacterial infections in the vagina.

Overdosing on foxglove can be fatal, as all parts of the plant are extremely poisonous. Contrary to a dangerous misconception, the toxic plant is not the source of a painkiller, but rather a powerful heart medication.

After a nearly 35-year hiatus in the introduction of new classes of antibiotics, linezolid was approved in 2000, representing a major breakthrough in the fight against resistant bacteria. The story of where did linezolid come from begins with early setbacks and pivots in pharmaceutical research during the late 20th century.

In December 1992, the U.S. Food and Drug Administration (FDA) first granted approval for the brand-name drug Taxol (paclitaxel) for the treatment of refractory ovarian cancer. The medication's journey from a rare tree bark to a life-saving chemotherapy, however, began decades earlier, marked by scientific breakthroughs, supply challenges, and significant milestones.

Amprenavir, marketed under the brand name Agenerase, was a protease inhibitor approved by the FDA in 1999 for the treatment of HIV. The direct answer to 'Is Amprenavir still available?' is no, as the medication was voluntarily removed from the U.S. market by its manufacturer over a decade ago. Its discontinuation was prompted by the development of a superior prodrug, which itself has also been phased out in favor of even newer, more advanced antiretroviral therapies.